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Connecting stakeholders across the healthcare ecosystem.
H1 was founded in 2017 by Ariel Katz (Founder) and Ian Sax (Founder).
H1 has raised $199.9M in total across 5 funding rounds.
H1 helps connect the healthcare ecosystem by providing a global platform of every healthcare professional and healthcare organization.
H1 was founded in 2017 by Ariel Katz (Founder) and Ian Sax (Founder).
H1 has raised $199.9M in total across 5 funding rounds.
H1's investors include Pauline Yang, Flex Capital, Goldman Sachs, IVP, Lead Edge Capital, Lux Capital, Menlo Ventures, Transformation Capital, Somesh Dash, Jean-Paul (J.P.) Sanday, Deena Shakir, Novartis dRx.
For an investment firm focused on healthcare, the mission typically centers on bridging diverse stakeholders—including startups, providers, payers, manufacturers, and patients—to accelerate innovation and improve healthcare outcomes. Their investment philosophy often emphasizes backing early to mid-stage companies that develop transformative medical devices, diagnostics, digital health solutions, and regenerative medicine technologies. Key sectors include cardiovascular, diagnostic monitoring, neurovascular, and digital health platforms. Such firms impact the startup ecosystem by providing not only capital but also strategic mentorship, industry connections, and access to a broad network of healthcare stakeholders, enabling startups to scale efficiently and bring products to market faster[1].
For a portfolio company within this ecosystem, the focus is on building innovative healthcare products such as AI-driven diagnostic tools, remote monitoring devices, or digital platforms that enhance patient engagement and clinical decision-making. These companies serve healthcare providers, patients, and payers by solving critical problems like early disease detection, improving access to care, or streamlining clinical workflows. Growth momentum is often demonstrated through clinical trial successes, regulatory approvals (e.g., CE marking, FDA designations), strategic partnerships, and funding rounds that fuel product development and market expansion[1][2][3].
Investment firms in healthcare often trace their founding to a desire to address fragmentation in the healthcare innovation landscape, typically established in the last decade by partners with deep industry experience in venture capital, healthcare operations, or medical technology. Over time, their focus evolves from pure financial investment to a more hands-on approach, integrating operational support and ecosystem-building to maximize portfolio impact.
Portfolio companies usually emerge from founders with clinical, engineering, or entrepreneurial backgrounds who identify unmet needs through direct healthcare experience or research. The idea often crystallizes around a pivotal moment—such as a clinical trial breakthrough or a technology validation—that validates the product concept and attracts early investor interest. Early traction may include pilot deployments, regulatory milestones, or initial revenue generation[1][2].
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These firms and companies ride the wave of digital transformation in healthcare, driven by trends like AI-powered diagnostics, telemedicine, personalized medicine, and value-based care. Timing is critical as healthcare systems globally seek scalable, data-driven solutions to improve outcomes and reduce costs. Market forces such as regulatory support for innovation, increasing patient demand for transparency, and advances in biotechnology favor these players. Their influence extends beyond product innovation to shaping healthcare delivery models and fostering collaboration across traditionally siloed stakeholders[3][4][7].
Looking ahead, investment firms will likely deepen their ecosystem integration, leveraging AI and data analytics to identify high-potential startups earlier and provide more customized support. Portfolio companies are expected to expand their product offerings, enhance interoperability, and pursue global market entry. Emerging trends such as neurotechnology, remote patient monitoring, and AI-driven clinical decision support will shape their trajectories. Their evolving influence will be pivotal in creating a more connected, efficient, and patient-centric healthcare ecosystem, fulfilling the promise of improved health outcomes through innovation[3][7]. This ongoing connectivity among stakeholders remains the cornerstone of transforming healthcare delivery and innovation.
Key people at H1.
H1 has raised $199.9M across 5 funding rounds. Most recently, it raised $23.0M Series C Extension in June 2022.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Jun 9, 2022 | $23.0M Series C Extension | ||
| Nov 16, 2021 | $100.0M Series C | Pauline Yang | Flex Capital, Goldman Sachs, IVP, Lead Edge Capital, Lux Capital, Menlo Ventures, Transformation Capital |
| Dec 17, 2020 | $58.0M Series B | Somesh Dash, Jean-Paul (J.P.) Sanday | Lead Edge Capital, Deena Shakir, Novartis dRx, Transformation Capital, YC |
| Apr 22, 2020 | $12.9M Series A | Greg Yap | Jeff Hammerbacher, Baron Davis Enterprises, Liquid 2 Ventures, Novartis dRx, Underscore VC |
| Oct 30, 2018 | $6.0M Other Equity | Ian Sax |