Oricell Therapeutics is a technology company.
Oricell Therapeutics has raised $193.0M across 3 funding rounds.
Oricell Therapeutics has raised $193.0M in total across 3 funding rounds.
Oricell Therapeutics has raised $193.0M in total across 3 funding rounds.
Oricell Therapeutics's investors include Qiming Venture Partners, RTW Investments.
Oricell Therapeutics is a clinical-stage biotechnology company developing innovative, affordable immunotherapies, primarily CAR-T cell therapies targeting unmet needs in oncology, such as relapsed or refractory multiple myeloma.[1][2][4] Its lead product, a GPRC5D-targeting autologous CAR-T therapy (Ori-C101), has received FDA IND approval (December 2023), NMPA IND approval (August 2023), and FDA Orphan Drug Designation (October 2022), with initial clinical data presented at ASCO and EHA 2022 and published in *The Lancet Haematology*.[1] The company serves patients with hematologic malignancies and solid tumors, addressing high costs and limited access to effective treatments through a cell therapy platform focused on efficacy and affordability.[3][4] Growth momentum includes over $120 million in Series B financing (August 2022), a pre-A round from Qiming Venture Partners (December 2019), and strategic partnerships like a $142 million bispecific antibody deal with Antengene (June 2022).[2]
Founded in February 2015 in Shanghai, Oricell Therapeutics emerged from a focus on pioneering cell therapy technologies to tackle global unmet needs in immunotherapy.[2][4] The company's backstory centers on building a proprietary platform for CAR-T and other immunotherapies, with early R&D results in liver cancer published in *Protein & Cell* (June 2018) and presentations at the 2018 Chinese Conference on Translational Medicine (October 2018).[2] Pivotal early traction came via a strategic cooperation with Beijing Yimiaoshenzhou Medical Technology (May 2018) and pre-A funding from Qiming Venture Partners (December 2019), fueling expansion into multiple myeloma and bispecific antibodies, marked by government recognitions like Shanghai's technology innovation funding (June 2022).[2]
Oricell rides the CAR-T and cell therapy wave in immuno-oncology, targeting solid tumors and blood cancers amid a market projected to grow rapidly due to rising cancer incidence and immunotherapy breakthroughs.[1][4] Timing aligns with global regulatory accelerations—FDA orphan designations and INDs signal faster paths to market—while China's biotech hub status (Shanghai Pudong) provides funding and talent advantages.[2] Market forces like affordability demands in emerging economies favor Oricell's model, influencing the ecosystem by partnering with firms like Cytiva and Antengene to scale manufacturing and global reach, potentially lowering barriers for next-gen therapies.[2]
Oricell is poised for Phase 1/2 trial readouts on Ori-C101, potential label expansions to other GPRC5D+ cancers, and bispecific antibody milestones, bolstered by its funding runway.[1][2] Trends like AI-optimized cell engineering, combo therapies, and China-US regulatory harmonization will shape its path, amplifying influence in affordable oncology. As a 2015 entrant scaling to global partnerships, Oricell exemplifies how focused innovation meets clinical urgency, positioning it to redefine accessible immunotherapies.[1][2][4]
Oricell Therapeutics has raised $193.0M across 3 funding rounds. Most recently, it raised $28.0M Venture Round in June 2025.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Jun 1, 2025 | $28.0M Venture Round | Qiming Venture Partners | |
| Feb 1, 2023 | $45.0M Series B | Qiming Venture Partners, RTW Investments | |
| Jul 1, 2022 | $120.0M Series B | Qiming Venture Partners |