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§ Venture Capital · New York City, NY, USA
Family office managing personal wealth with a macro-driven investment strategy focused on public equities, tech, and healthcare.
Duquesne Capital is a Pittsburgh, Pennsylvania-based investment firm that operates as a family office utilizing a top-down, macro-driven strategy to allocate assets across global equities, liquidity cycles, and central bank policies. Originally structured as a hedge fund, the firm historically delivered average annual returns of 30 percent with no losing years before returning outside capital and closing with over $12 billion in assets in 2010. Operating exclusively to manage its founder's wealth, the entity currently oversees approximately $8 billion in total assets under management. As of the first quarter of 2025, the firm's public equity portfolio is valued at $3.06 billion and features significant positions in recognizable technology and healthcare companies such as Taiwan Semiconductor, Coupang, DocuSign, Teva Pharmaceutical, and Natera. Duquesne Capital was founded in 1981 by former Quantum Fund portfolio manager Stanley Druckenmiller.
Duquesne Capital has 1 tracked investment across 1 company. The latest tracked deal is $20.0M Series A in Ratio Therapeutics in February 2023.
| Date | Company | Round | Lead Investor(s) | Co-Investor(s) |
|---|---|---|---|---|
| Feb 1, 2023 | Ratio Therapeutics | $20.0M Series A | Duquesne Capital, Schusterman Family Investments | — |