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Lynne Chou O'Keefe is the Founder and Managing Partner of Define Ventures in the United States. Her early-stage venture capital firm focuses exclusively on digital health startups across incubation, seed, Series A, and Series B rounds, currently managing $800 million in assets across 24 portfolio companies. Before establishing Define Ventures, she served as a Senior Partner at Kleiner Perkins and held product marketing leadership roles at Abbott Vascular, where she launched more than ten medical technologies globally. Earlier in her career, she worked in software venture capital at Apax Partners and mergers and acquisitions at Goldman Sachs, after earning an MBA from Harvard Business School and a BS from Stanford University. Today, her investment strategy centers on scaling transformative healthcare technologies, evidenced by her involvement with prominent digital health companies including Livongo and Hims & Hers.
Lynne Chou O'Keefe stands as a prominent figure in the venture capital landscape, particularly recognized for her profound impact on healthcare innovation. As a Managing Partner at Define Ventures, she plays a pivotal role in shaping the future of healthcare and enterprise technology through strategic early-stage investments. Her leadership helps guide the firm's vision, identifying and nurturing companies poised for significant disruption and growth.
At Define Ventures, Lynne's investment focus is sharply honed on the intersection of technology and healthcare. She actively seeks out groundbreaking companies in digital health, healthcare technology, and enterprise software, often at the seed or Series A stage. Her portfolio interests include virtual care platforms, mental health solutions, AI-driven diagnostics, precision medicine, and data analytics tools that promise to enhance patient outcomes, streamline operations, and improve accessibility within the healthcare ecosystem. She is particularly drawn to founders who are building scalable, impactful solutions that address critical unmet needs.
Lynne's extensive career background provides her with a unique and invaluable perspective in venture capital. Before co-founding Define Ventures, she served as a General Partner at Kleiner Perkins, where she was instrumental in building and leading their digital health practice. This experience allowed her to cultivate a deep understanding of the challenges and opportunities within the evolving healthcare sector. Prior to her venture capital roles, Lynne held significant positions at Abbott Ventures, Johnson & Johnson, and Guidant, gaining hands-on operational and corporate venture experience. Her early career in biomedical engineering further solidified her technical foundation, enabling her to critically evaluate complex technologies and their market potential. This blend of operational, corporate venture, and pure venture capital experience makes her a highly sought-after partner for entrepreneurs.
Lynne Chou O'Keefe's commitment extends beyond capital investment; she is known for her hands-on approach, providing strategic guidance and mentorship to her portfolio companies. Her ability to identify promising startups and help them navigate the complexities of the healthcare market has cemented her reputation as a visionary investor dedicated to fostering innovation that truly makes a difference.
Lynne Chou O’Keefe is a Managing Partner at Define Ventures, a leading venture capital firm. She is a prominent investor specializing in early-stage digital health, healthcare technology, and enterprise software companies.
Lynne Chou O’Keefe primarily invests in early-stage companies focused on digital health, healthcare technology, AI in healthcare, and enterprise software. She seeks innovative solutions that aim to transform healthcare delivery and efficiency.
Lynne Chou O’Keefe works as a Managing Partner at Define Ventures, a venture capital firm dedicated to early-stage investments in the healthcare and enterprise technology sectors.
