UpStream Care is a technology company.
UpStream Care has raised $140.0M across 1 funding round.
UpStream Care has raised $140.0M in total across 1 funding round.
UpStream Care is a healthcare technology company founded in 2019 and headquartered in Greensboro, North Carolina, that provides in-practice support programs for primary care physicians, focusing on pharmacist-led care models to improve patient outcomes for seniors and reduce hospital admissions.[1][4] It serves primary care providers and their patients by embedding clinical teams and deploying technology solutions that empower physicians, enhance care coordination, and drive value-based care, with a Series B stage raising $185M total, including a $140M round two years ago.[1][4] The company has demonstrated growth momentum through rapid expansion to over 3,000 physicians, partnerships like Innovaccer Health Cloud for data activation, and tools for provider network management, though it faced a setback with 66 layoffs in August 2024 following a contract termination by ACO Triad HealthCare Network.[1][3][4]
UpStream Care was founded in 2019 in Greensboro, North Carolina, amid a push for value-based care models in U.S. healthcare, specifically targeting support for primary care physicians managing complex senior populations.[1][3] Key details on founders are not specified in available sources, but the company emerged with a focus on pharmacist-led, in-practice programs to address physician burdens like care coordination and hospital readmissions, building early traction through technology integrations and provider onboarding.[1][3] Pivotal moments include securing $45M in early funding to embed clinical teams with physicians, a $140M Series B led by Coatue, Dragoneer, and others to scale nationally, and adopting platforms like Innovaccer Health Cloud and V12 Network for efficient network growth to 3,000+ physicians, achieving 100% faster provider activation and 80% higher satisfaction.[3][4][5]
UpStream Care stands out in primary healthcare through these key strengths:
UpStream Care rides the value-based care trend in U.S. healthcare, where payers and providers shift from fee-for-service to outcome-driven models amid rising senior populations and cost pressures.[1][3] Timing aligns with post-2020 accelerations in telehealth, data interoperability, and AI-enabled care coordination, amplified by Medicare Advantage growth and ACO expansions.[1][4] Market forces favoring it include demand for pharmacist augmentation in primary care shortages, regulatory pushes for reduced readmissions, and tech stacks enabling population health analytics—evident in its Innovaccer and V12 integrations.[3][4] It influences the ecosystem by scaling physician enablement, supporting life sciences and payers in patient management, and modeling hybrid tech-service hybrids, though contract disputes highlight execution risks in fragmented health systems.[1]
UpStream Care's path forward hinges on leveraging its $185M war chest to rebuild post-2024 layoffs, expand pharmacist-led models nationally, and deepen AI/data integrations for predictive care amid aging demographics.[1][4] Trends like AI-driven population health (e.g., Bridgit-like tools) and ACO consolidations will shape it, potentially evolving its influence from physician support to full-stack value-based platforms if it navigates payer disputes.[1][2][3] Watch for partnerships amplifying its 3,000-physician network, positioning it to transform senior care scalability.[3][4]
UpStream Care has raised $140.0M in total across 1 funding round.
UpStream Care's investors include ARCH Venture Partners, Cambridge Innovation Capital, Define Ventures, Dragoneer Investment Group, Ben Robbins, HealthCap, Mubadala, Ayman AlAbdallah.
UpStream Care has raised $140.0M across 1 funding round. Most recently, it raised $140.0M Series B in November 2022.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Nov 1, 2022 | $140.0M Series B | ARCH Venture Partners, Cambridge Innovation Capital, Define Ventures, Dragoneer Investment Group, Ben Robbins, HealthCap, Mubadala, Ayman AlAbdallah |