
PFM Health Sciences
PFM Health Sciences is an investment management firm specializing in global healthcare strategies.
Financial History
Leadership Team
Key people at PFM Health Sciences.

PFM Health Sciences is an investment management firm specializing in global healthcare strategies.
Key people at PFM Health Sciences.
PFM Health Sciences is an investment management firm specializing in global healthcare strategies, with a mission to generate long-term capital appreciation by investing in innovative companies across biopharma, medical technology, life sciences, and healthcare services. The firm’s investment philosophy centers on deep sector specialization, bottom-up fundamental research, and active risk management, allowing it to identify secular growth trends and capitalize on transformative opportunities. PFM Health Sciences maintains diversified exposure across public and private markets, investing across the capital structure to maximize capital efficiency and foster collaboration. Its focus on sustainable impact and responsible stewardship positions it as a key player in shaping the future of healthcare innovation and supporting the growth of startups and emerging companies in the sector.
Founded in 2004 and headquartered in San Francisco, PFM Health Sciences was established by Brian Grossman, who serves as Founding Partner and Chief Investment Officer. Grossman’s background in healthcare investing and his vision for a specialized, research-driven approach laid the foundation for the firm’s unique positioning. Over the years, PFM Health Sciences has evolved from a boutique advisor into a leading healthcare investment manager, expanding its reach and influence by partnering with innovative companies and institutional investors. The firm’s affiliation with AMG (Affiliated Managers Group) since 2016 has further strengthened its resources and global footprint, enabling it to scale its strategies and deepen its impact across the healthcare ecosystem.
PFM Health Sciences is riding the wave of a powerful, secular healthcare innovation cycle, driven by advances in biotechnology, digital health, AI, and data analytics. The convergence of technology and healthcare is transforming drug discovery, patient care, and operational efficiency, creating unprecedented investment opportunities. Demographic trends, such as aging populations and rising healthcare costs, further amplify the demand for innovative solutions. By focusing on companies that leverage these trends, PFM Health Sciences not only generates strong returns but also accelerates the adoption of technologies that improve health outcomes and reshape the delivery of care. Its influence extends beyond financial returns, contributing to the broader ecosystem by supporting startups and fostering collaboration across the healthcare and technology sectors.
Looking ahead, PFM Health Sciences is well-positioned to continue capitalizing on the rapid pace of healthcare innovation. As new technologies like AI, genomics, and digital therapeutics mature, the firm’s specialized approach and flexible investment model will be increasingly valuable in identifying and nurturing the next generation of breakthrough companies. The growing emphasis on sustainability and measurable impact will further align with PFM Health Sciences’ mission, attracting both institutional capital and entrepreneurial talent. In a landscape defined by disruption and transformation, PFM Health Sciences stands out as a catalyst for change, shaping the future of healthcare and driving long-term value for investors and society alike.
Key people at PFM Health Sciences.