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§ Private Profile · 2101 Cottontail Ln, Somerset, New Jersey, 08873, United States
Legend Biotech is a company.
Legend Biotech has raised $150.5M across 1 funding round.
Key people at Legend Biotech.
Legend Biotech has raised $150.5M in total across 1 funding round.
Legend Biotech is a global, commercial-stage biotechnology company developing, manufacturing, and commercializing novel cell therapies. Its core focus is innovative cell therapy treatments for oncology, particularly addressing hematologic malignancies and solid tumors. The company utilizes advanced technologies, including in vivo and allogeneic CAR-T therapies, to create these solutions.
Established in 2014, Legend Biotech originated as the 'Legend Project,' an early cell therapy initiative within GenScript. Frank Fan founded the company, which spun out to specifically advance cell therapy research and development. This separation leveraged initial insights from GenScript, allowing a focused pursuit of groundbreaking CAR-T technology.
Legend Biotech provides advanced cell therapy treatments to patients and healthcare providers facing life-threatening diseases, predominantly cancers. Its vision emphasizes continuous exploration and discovery to deliver innovative options. The company is dedicated to treating and curing severe illnesses through pioneering therapeutic approaches, striving to advance medical science.
Legend Biotech has raised $150.5M across 1 funding round. Most recently, it raised $150.5M Series A in April 2020.
| Date | Round | Lead Investors | Other Investors | Status |
|---|---|---|---|---|
| Apr 11, 2020 | $150.5M Series A | — | Hudson BAY Capital, Johnson & Johnson Innovation, Lilly Asia Ventures, RA Capital Management, Vivo Capital | Announced |
Legend Biotech is a global, commercial-stage biotechnology company specializing in the discovery, development, manufacturing, and commercialization of novel cell therapies, primarily CAR-T therapies for oncology.[1][2][3] It focuses on treating hematologic malignancies like multiple myeloma and expanding into solid tumors, serving patients with intractable diseases through innovative platforms including CAR-T, CAR-NK, CAR-γδ T, and non-gene-editing CAR technologies.[2][3][4] The company solves unmet needs in cancer treatment by advancing therapies like CARVYKTI® (ciltacabtagene autoleucel, co-developed with Janssen), with strong growth shown in recent data presentations at ASH 2025, new facility openings, and global expansions as of late 2025.[3]
Its mission is to transform lives through innovative cell therapies, pursuing cures for life-threatening diseases, while its vision positions it as a global leader in cell and gene therapy.[1][4][5]
Legend Biotech was founded in 2014 as an early-stage cell therapy company by visionary scientists with expertise in immunology and gene editing, initially operating as the "Legend Project" in a small space targeting multiple myeloma therapies.[2][6] The idea emerged from recognizing the potential of antibody-based therapeutics, leading to breakthroughs like producing nanobodies and pioneering CAR-T cells targeting the BCMA protein—one of the first worldwide—in 2015.[2]
Pivotal moments included investigator-initiated trials in China in 2016, data presentations at ASCO in 2017 that secured a key partnership with Janssen Biotech for co-developing cilta-cel, and evolution into a fully integrated, global commercial-stage company by 2025 with expanded pipelines and manufacturing.[2][3]
Legend Biotech rides the explosive growth in cell and gene therapy, a trend accelerated by successes in CAR-T for blood cancers amid rising cancer incidence and demand for personalized medicine.[1][3] Timing is ideal post-2020s regulatory approvals for CAR-T therapies, with market forces like aging populations, refractory cancer challenges, and investments in biotech manufacturing favoring its global footprint across the US, China, and Europe.[2][4][6]
It influences the ecosystem by co-developing standards like CARVYKTI®, expanding access via new facilities and approvals, and pioneering next-gen platforms that could cure solid tumors, shaping competition and investor interest in oncology biotech.[3][4]
Legend Biotech is poised for accelerated growth through pipeline advancements, with 9 ASH 2025 presentations signaling robust data in multiple myeloma and novel platforms, plus expansions like its Philadelphia facility and J.P. Morgan Healthcare Conference presence in December 2025.[3] Trends like AI-driven therapy design, global manufacturing scale-up, and combination therapies will propel it toward broader indications in solid tumors and autoimmune diseases.
Its influence may evolve from CAR-T pioneer to diversified cell therapy leader, potentially dominating intractable disease markets if manufacturing and access hurdles are cleared—reinforcing its mission to deliver hope through curative innovations.[1][2][4]
Key people at Legend Biotech.
Legend Biotech has raised $150.5M in total across 1 funding round.
Legend Biotech's investors include Hudson Bay Capital, Johnson & Johnson Innovation, Lilly Asia Ventures, RA Capital Management, Vivo Capital.