Human Augmentation Syndicate

ActiveVenture Capital

Updated: Dec 5, 2025 ·

Financial History

Total Raised

N/A

Valuation

N/A

Investments Made

Date	Company	Round	Lead Investor(s)	Co-Investor(s)
Sep 1, 2024	Kindlee	$120K Seed	—	Techstars, Zero Capital, Alexander Torrenegra, John M. Mueller
Apr 1, 2024	Take2 AI	$5.0M Seed	—	Floodgate, Forum Ventures, Kalei Ventures, Reach Capital, SemperVirens Venture Capital, Cat Hernandez, Armando Mann
Apr 1, 2024	Ryse	$500K Seed	—	Accel, Avalancha Ventures, Buckley Ventures, Cowboy Ventures, E14 Fund, Felix Capital, Floodgate, March Capital, Nyca Partners, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Seven Seven Six, Howard Lindzon, Susa Ventures, Greg Bettinelli, The Hit Forge, Transmedia Capital, Y Combinator, Andrew Bialecki, Eric Ries, John Fontein, Josh Spear, Michael Birch, Nico Rosberg, Sean Park
Nov 1, 2023	Manifold	$15.0M Series A	—	Accel, Avalancha Ventures, Benchmark, Buckley Ventures, Cowboy Ventures, E14 Fund, Felix Capital, Floodgate, Founders Fund, Long Journey Ventures, March Capital, Mayfield, Nyca Partners, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Seven Seven Six, Signia Venture Partners, Howard Lindzon, Susa Ventures, Talis Capital, Greg Bettinelli, The Hit Forge, Tiger Global Management, TQ Ventures, Transmedia Capital, Y Combinator, Aleksander Leonard Larsen, Cato Sælid, Eric Ries, Eugene Wei, John Fontein, Josh Spear, Julius Genachowski, Kevin Lin, Michael Birch, Nico Rosberg, Sahin Boydas, Sean Park, Xen Lategan
Sep 1, 2023	IOMED	$11.0M Series A	—	Adara Ventures, Ada Ventures, Scalebridge Capital, Alan MacIntosh, Charlie Songhurst, Evan Cheng
Jun 1, 2023	BIOS	$20.0M Series A	—	7GC & Co, Ada Ventures, Builders, Friedom Partners, FTX Ventures, GoAhead Ventures, Innovation Endeavors, Lakeside Capital, Scalebridge Capital, Spark Capital, SparkLabs Group, Adeel Hussain, Alan MacIntosh, Charlie Songhurst, Dustin Moskovitz, Elia Montanari, Evan Cheng, Ishani Patel, Jaan Tallinn, Jason Haider, Preetha Parthasarathy, Siddharth Singhal, Vikas Sabnani
May 1, 2023	SellerX	$64.0M Venture Round	—	83North, Accel, Aleph VC, Avalancha Ventures, Buckley Ventures, Cherry Ventures, Cowboy Ventures, E14 Fund, Felix Capital, Floodgate, General Catalyst, Hitachi Ventures, iGlobe Partners, L Catterton Growth, Lifeline Ventures, March Capital, Nyca Partners, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Seven Seven Six, Howard Lindzon, Spark Capital, Susa Ventures, Greg Bettinelli, The Hit Forge, Transmedia Capital, Y Combinator, Andrew Bialecki, Eric Ries, John Fontein, Josh Spear, Michael Birch, Nico Rosberg, Sahin Boydas, Sean Park, Yechiel Engelhard
Mar 1, 2023	Videowise	$3.0M Seed	—	Acadian Ventures, Accel, Andreessen Horowitz, Anthemis Group, Arkitekt Ventures, Bedrock Capital, Bling Capital, BoxGroup, Cambrian Ventures, Connect Ventures, Conversion Capital, Emergence Capital, Encomenda Smart Capital, Founder Collective, Founders Future, Gecad Ventures, Highland Capital Partners, Indeed.com, iNovia Capital, Jude Gomila Rolling Fund, Kearny Jackson, Kindred Ventures, LifeX Ventures, monashees, NFX, Northside Ventures, Republic Capital, Salesforce Ventures, Slack Fund, SNR, SV Latam Fund, TheVentureCity, Tusk Venture Partners, TY, Ulu Ventures, Weekend Fund, Ed Baker, Elliott Cohen, Eric Nadalin, Garrett Koehn, Gokul Rajaram, Greg Kidd, Javier Olivan, Sam Altman, Scott Belsky, Sean Glass
Feb 1, 2023	Magma	$3.0M Seed	—	ACME Capital, AngelList, Canaan Partners, Catapult Capital, General Catalyst, Matrix, Quiet Capital, Jonathan Swanson, Sam Shank, Shervin Pishevar, Yan-David Erlich
Sep 1, 2022	HopSkipDrive	$37.0M Series D	—	01 Advisors, 1776, Accel, Afore Capital, Aleph VC, Alumni Ventures, Amplify Partners, Anderson Angels, Andreessen Horowitz, Avalancha Ventures, Backend Capital, Bascom Ventures, Basecamp Fund, Blisce, Buckley Ventures, Contour Venture Partners, Cowboy Ventures, DBL Partners, Dimension Capital, Draper Associates, E14 Fund, Energy Impact Partners, Jenny Fielding, Scott Hartley, Family Office, Felix Capital, FirstMark Capital, Floodgate, Flucas Ventures, Gotham Gal Ventures, Gradient Ventures, Great Oaks Venture Capital, Humba Ventures, Infinite Niches, Left Lane Capital, March Capital, Modern Venture Partners, Montage Ventures, Moxxie Ventures, Nyca Partners, Otherwise Fund, Parkway VC, Prototype Capital, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Scribble Ventures, Seven Seven Six, Shrug Capital, SignalFire, Howard Lindzon, Sound Ventures, Stage 2 Capital, Streamlined Ventures, Susa Ventures, SV Angel, Greg Bettinelli, TCG (The Chernin Group), The Hit Forge, Transmedia Capital, Tusk Venture Partners, VZVC, Weekend Fund, What If Ventures, XFactor Ventures, Y Combinator, Alain Hanover, Alper Kiresepi, Andrew Bialecki, Anna Patterson, Chad Nitschke, Charlie Songhurst, Daria Derkach, Erick Miller, Eric Ries, Farzad Nazem, Howard Charney, Ian McNish, John Fontein, Josh Spear, Kevin Weil, Michael Birch, Moshe Lifschitz, Nico Rosberg, Peter Hunn, Richard Cooperstein, Rudra Peram, Sahin Boydas, Sean Park, Tyler Willis, Yagiz Sozmen, Zach Segal
Sep 1, 2022	Fuse Energy	$79.0M Venture Round	—	468 Capital, Accel, Avalancha Ventures, Balderton Capital, BP Ventures, Breakthrough Energy Ventures, Buckley Ventures, Cowboy Ventures, DST Global, E14 Fund, Felix Capital, Floodgate, Flucas Ventures, General Catalyst, Global Founders Capital, Greenoaks Capital, Index Ventures, La Famiglia, Left Lane Capital, Lightspeed Venture Partners, Lowercarbon Capital, Luv Ventures, March Capital, Meritech Capital Partners, Northzone, Nyca Partners, Picus Capital, Prosus Ventures, QED Investors, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Seven Seven Six, Singular, Howard Lindzon, Susa Ventures, Greg Bettinelli, TCV, The Hit Forge, Transmedia Capital, Valar Ventures, Y Combinator, Andrew Bialecki, Anselm Bauer, Benjamin Guenther, Eric Ries, Ingo Uytdehaage, John Fontein, Josh Spear, Max-Josef Meier, Michael Birch, Sahin Boydas, Sean Park, Sebastian Schuon
Jul 1, 2022	Mable (Neurolytic Healthcare)	$3.0M Seed	—	Background Capital, LifeX Ventures, Bobby Lo
Jun 1, 2022	Next Matter	$16.0M Series A	—	Andreessen Horowitz, BlueYard Capital, Crane Venture Partners, Bjorn Kolbmuller, Fredrik Hjelm, Kai Huang, Lukas Brosseder, Mario Götze, Maximilian Tayenthal, Paul Schwarzenholz, Tony Jamous, Verena Pausder
May 1, 2022	Sheetgo	$2.0M Seed	—	Coinbase Ventures, Draper B1, Greylock, Jett Fein, Outrun Ventures, Redpoint Ventures, Renegade Partners, XYZ Venture Capital, Akshay Kothari, Brandon Leonardo, Javier Olivan, Max Mullen
Mar 1, 2022	Hermeus	$100.0M Series B	—	ACME Capital, ATX Venture Partners, Canaan Partners, Catapult Capital, Draper Associates, Embedded Ventures, Founders Fund, Gaingels, Khosla Ventures, MarsBio, Matrix, Piva Capital, Playground Global, Quiet Capital, Revolution, Sommet AB, Aayush Phumbhra, Jonathan Swanson, Sahin Boydas, Sam Shank, Shervin Pishevar, Yan-David Erlich
Mar 1, 2022	doxo	$19.0M Series C	—	Endeavor Catalyst, Jackson Square Ventures, Rumbo Ventures, Wildcat Ventures, Alexander Torrenegra, Fredrik Björk, Manolo Atala, Mike Hennessey, Wences Casares
Feb 1, 2022	Aside	$17.0M Series A	—	1776, 305 Ventures, Accel, ACME Capital, AIX Ventures, Altair Capital Management, AME Cloud Ventures, American Express Ventures, Andreessen Horowitz, Animoca Brands, Ardent Venture Partners, Arrive, Astanor Ventures, Atlantic Bridge University Fund, Bain Capital Ventures, Balderton Capital, Bennu, Better Capital, Better Tomorrow Ventures, BITKRAFT Ventures, Bling Capital, Blossom Capital, Bond, Browder Capital, C2 Investment, Canvas Ventures, Casa Verde Capital, Cherubic Ventures, Coatue, Cometa, Construct Capital, CRV, Curie.Bio, Draper Associates, DTX Ventures, Emergence Capital, Endeavor Catalyst, Jenny Fielding, Scott Hartley, Expa, Exponent Founders Capital, Fifth Wall, FJ Labs, Flex Capital, Forerunner Ventures, Founder Collective, Founders Fund, Four Rivers Group, Franklin Templeton Investments, Fyrefly VC, GAIN, Gaingels, General Atlantic, General Catalyst, Giant Ventures, Gigascale Capital, Gradient Ventures, Great Oaks Venture Capital, Greylock, Hardware Club, Heavybit, Horizon 3 Venture Studio, Insight Partners, Interplay Ventures, Khosla Ventures, La Famiglia, LGF, Locus Ventures, Lux Capital, Jared Hecht, Market One Capital, Mischief Venture Capital, Moonshots Capital, Glenn Solomon, Oren Yunger, On Deck, One Planet Group, Operator Partners, Operator Ventures, Otherwise Fund, Pear VC, Precursor Ventures, QED Investors, QueensBridge Venture Partners, Quiet Capital, Ravelin Capital, Redpoint Ventures, Ribbit Capital, Richmond Global Ventures, Sarona Ventures, SciFi VC, Sequoia Capital, Sherpa Ventures, Silicon Valley Connect, Silicon Ventures, SoftBank Investment Advisers, Sound Ventures, Storm Ventures, Streamlined Ventures, Summit Partners, SV Angel, TenOneTen Ventures, Tet Ventures, ThirdLove, Thirty Five Ventures, TMV, Todd and Rahul's Angel Fund, Tuesday Capital, Uncorrelated Ventures, UpHonest Capital, Walden International, Webb Investment Network, Y Combinator, Aaron Levie, Adam Gross, Adrian Aoun, Akshay Kothari, Amit Agarwal, Amy Chang, Armando Mann, Assaf Wand, Augusto Marietti, Baron Davis, Biz Stone, Christian Oestlien, Chris Wang, Cristina Cordova, Curtis Lee, David Petersen, David Peterson, Diogo Teles, Dylan Field, Eddie Hartman, Elliot Shmukler, Emmett Shear, Eoghan McCabe, Eric Wei, Eric Wu, Evan Brown, George Hu, Gerald Parloiu, Gina Bianchini, Girish Mathrubootham, Gokul Rajaram, Greg Tseng, Harris Barton, Hunter Horsley, Immad Akhund, James Park, Jason Robins, Jenna Hannon, Jeremy Cai, Jesse Leimgruber, Joshua Reeves, Karim Atiyeh, Kathleen Hale, Kevin Lin, Kevin Weil, Kunal Shah, Luke Sherwin, Mark Cuban, Mark Pincus, Matias Woloski, Neil Parikh, Nick Hunley, Pamela Valdes, Samvit Ramadurgam, Saturnin Pugnet, Scott Belsky, Scott Kleper, Sebastian Gil, Sebastien Borget, Shervin Pishevar, Sohail Prasad, Steve Chen, Tony Xu, Venus Williams, Vivek Patel
Feb 1, 2022	Reveri	$4.0M Seed	—	Arkitekt Ventures, Background Capital, bloom venture partners, Broadway Angels, Merline Saintil, General Catalyst, InReach Ventures, LifeX Ventures, Max Ventures, Operator Collective, The General Partnership, Trust Ventures, Aston Motes, Bobby Lo, Mantas Mikuckas, Nick Caldwell
Jan 1, 2022	Plexigrid	$2.0M Seed	—	Anthemis Group, Encomenda Smart Capital, LifeX Ventures, NFX, TheVentureCity, Greg Kidd, Javier Olivan
Jan 1, 2022	Novo	$90.0M Series B	—	Accel, AngelList, Avalancha Ventures, Benchmark, Brighton Park Capital, Buckley Ventures, Cowboy Ventures, Crosslink Capital, Cyberstarts VC, DST Global, E14 Fund, Felix Capital, Floodgate, Founders Fund, Fuel Ventures, Greycroft, Hetz Ventures, Insight Partners, March Capital, Mars Growth Capital, Nyca Partners, Presight Capital, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Sapphire Ventures, Seven Seven Six, Howard Lindzon, Susa Ventures, Greg Bettinelli, The Hit Forge, Transmedia Capital, Valar Ventures, Y Combinator, Abhinav Asthana, Andrew Bialecki, Ben Bernstein, Danny Hadar, Eric Ries, Erik Podzuweit, Florian Prucker, John Fontein, Josh Spear, Mato Peric, Michael Birch, Nico Rosberg, Oliver Jung, Philippe Teixeira da Mota, Sahin Boydas, Sean Park, Yevgeny Dibrov
Dec 1, 2021	Stocktwits	$30.0M Series B	—	20VC, Accel, AngelList Syndicator, Antler, Avalancha Ventures, Buckley Ventures, Cowboy Ventures, E14 Fund, Felix Capital, Floodgate, Foundry Group, March Capital, Nyca Partners, QueensBridge Venture Partners, Rainfall Ventures, Relay Ventures, Seven Seven Six, Social Leverage, Susa Ventures, Greg Bettinelli, Luke Beatty, The Hit Forge, Transmedia Capital, True Ventures, Y Combinator, Andrew Bialecki, Chris Murphy, Darius Contractor, Eric Ries, Jan Deepen, Jeremy Yap, John Fontein, Josh Spear, Michael Birch, Nico Rosberg, Pete Koomen, Sahin Boydas, Sean Park, Shane Neman, Stefan Jeschonnek
Dec 1, 2021	Kueski	$100.0M Series C	—	10X Capital, 2.12 Angels, Accel, Altai Ventures, Jean de Fougerolles, B Capital Group, Coatue, Coinbase Ventures, Cometa, Endeavor Catalyst, Equity Alliance, Felicis Ventures, Flexcap, Flex Capital, GAIN, INBlockchain, Lightspeed India Partners, Magma Partners, Morpheus Ventures, Pareto Holdings, Shailendra Singh, Preston-Werner Ventures, Recharge Capital, Revel Partners, Richmond Global Ventures, Todd and Rahul's Angel Fund, Tuesday Capital, White Star Capital, Y Combinator, Anthony Pompliano, Augusto Marietti, Ben Tossell, Christopher Golda, Faizan Khan (Unchained Capital), Kevin Weil, Mei Z., Scott Belsky
Nov 1, 2021	Yaba	$17.0M Series A	—	Draper B1, Outrun Ventures, Andreas Mihalovits
Oct 1, 2021	Bondaval	$7.0M Seed	—	20VC, ActivumSG, Bascom Ventures, Day One Ventures, Draper B1, Element Ventures, Entrepreneur First, Expa, Frontier Dawn Partners, Indicator Ventures, MMC Ventures, MS&AD Ventures, Oak HC/FT, Octopus Ventures, Outrun Ventures, Pareto Holdings, Passion Capital, Point Nine Capital, Hayden Simmons, Saga, Shasta Ventures, SNR, Stride VC, TrueSight Ventures, Abakar Saidov, Andreas Mihalovits, Azeem Azhar, Charles Delingpole, Charlie Songhurst, Chris Murphy, Gordon Wintrob, Ian Hogarth, Immad Akhund, Javier Olivan, Jonathan Siegel, Marc McCabe, Oleg Rogynskyy, Richard Fearn, Richard Talbot, Sean Harper, Tom Blomfield, William Tunstall-Pedoe, Yi Luo, Zachary Sims
Oct 1, 2021	Matter	$7.0M Series A	—	01 Advisors, Kevin Hartz, A* Capital (A Star Capital), Boost VC, BoxGroup, DCM, Defy Partners, Felicis Ventures, Felix Capital, Flex Capital, Floodgate, Freestyle Capital, General Catalyst, Generative Ventures, M.G. Siegler, GV, LGF, Liquid 2 Ventures, Long Journey Ventures, Nyca Partners, Operator Collective, Outrun Ventures, Pareto Holdings, Project A, Seven Seven Six, TDK Ventures, Techstars, The General Partnership, Turing Capital, Vayner RSE, Wave Capital, XFactor Ventures, Y Combinator, Aaron Harris, Adam Goldstein, Andy Coravos, Balaji Srinivasan, Bangaly Kaba, Charlie Cheever, Chris Bennett, Claire Hughes Johnson, Emil Lee, Eoghan McCabe, Eric Chernoff, Eric Ries, Greg Isenberg, John Johnson, Julia Hartz, Louis Beryl, Matt Mazzeo, MG Siegler, Michael Dell, Rick Berry, Ryan Orr, Trevor McFedries, Wiley Cerilli, Will Brooks, William Mougayar, Will Martin

Financial History

Total Raised

N/A

Valuation

N/A

Leadership Team

Key people at Human Augmentation Syndicate.

Ariel Poler

Founder

Leadership Team

Key people at Human Augmentation Syndicate.

Ariel Poler

Founder

Deep Dive

High-Level Overview

The Human Augmentation Syndicate is an AngelList-based investment syndicate focused on backing early-stage startups that are building technologies to enhance human capabilities. Its mission is to accelerate the development of human augmentation—technologies that extend, restore, or upgrade human physical, cognitive, and sensory functions—by connecting visionary founders with experienced angel investors and strategic partners.

The syndicate’s investment philosophy centers on the belief that the next decade will be defined by breakthroughs in neural interfaces, bioelectronics, wearable systems, and AI-driven health technologies. It targets companies in core human augmentation domains such as neurotechnology, prosthetics, exoskeletons, brain-computer interfaces, and digital health platforms. By concentrating on this frontier, the syndicate plays a catalytic role in shaping a new wave of startups that sit at the intersection of biology and technology, helping to de-risk and scale innovations that have the potential to redefine healthcare, work, and daily life.

Origin Story

The Human Augmentation Syndicate was founded by Ariel Poler, a seasoned entrepreneur and investor with deep roots in technology and innovation. Poler launched the syndicate on AngelList as a thematic vehicle to channel capital and expertise into startups pioneering human augmentation technologies. His background and network in deep tech and health innovation positioned him to identify early signals in fields like neural engineering and bio-augmentation.

The syndicate gained early visibility through its lead participation in BIOS’ $4.5M seed round in 2018, marking BIOS as the first company in the world to automate the identification of neural signals regulating organ function. This investment underscored the syndicate’s focus on foundational, platform-like technologies rather than narrow point solutions. Since then, it has become a signal investor for startups working on “Human 2.0” technologies, attracting co-investors from top-tier funds and strategic angels who share its conviction in the transformative potential of human augmentation.

Core Differentiators

Thematic Focus on Human Augmentation: Unlike generalist syndicates, it specializes in a high-conviction theme—technologies that directly interface with or enhance the human body and mind, including neural interfaces, implantables, wearables, and AI-driven health tools.

Founder-Operator DNA: Led by Ariel Poler, the syndicate benefits from operator-level insight into deep tech and health innovation, allowing it to provide more than just capital—offering strategic guidance on product development, regulatory pathways, and commercialization.

Access to Cutting-Edge Deals: The syndicate has secured lead or anchor positions in high-potential, technically complex startups like BIOS, giving its backers access to deals that are often oversubscribed or difficult for individual angels to access.

Network Leverage: It draws in co-investors from top funds (e.g., Real Ventures, AME Cloud Ventures) and prominent angels, creating a powerful network effect that amplifies deal flow, credibility, and follow-on funding opportunities for portfolio companies.

Signal in a Nascent Field: In a space still emerging from research labs into commercial products, the syndicate acts as an early validator, helping to legitimize and accelerate companies that are building the infrastructure layer for human augmentation.

Role in the Broader Tech Landscape

The Human Augmentation Syndicate is riding the convergence of several powerful trends: the maturation of neural engineering, the miniaturization of bioelectronics, the rise of AI in healthcare, and the growing demand for technologies that extend human performance and longevity. These forces are fueling what is increasingly being called the “Human 2.0” era, where technology is no longer just external tools but integrated into the body and nervous system.

Timing is critical: as regulatory pathways for implantables and neural devices begin to clarify (e.g., FDA’s increased engagement with neurotech), and as aging populations drive demand for assistive and restorative technologies, the market for human augmentation is expanding rapidly. The syndicate sits at the heart of this shift, backing companies that are building the foundational interfaces—like neural “USB ports for the body”—that will enable future applications in prosthetics, organ control, mental health, and beyond.

By focusing on platform technologies rather than isolated applications, the syndicate helps shape an ecosystem where multiple use cases can emerge from a single interface layer. This positions it not just as a passive investor, but as an architect of the human augmentation stack, influencing how startups approach design, data, and clinical validation in this emerging field.

Quick Take & Future Outlook

Looking ahead, the Human Augmentation Syndicate is well-positioned to become a defining node in the human augmentation ecosystem. As neural interfaces, bioelectronics, and AI-driven health tools move from labs to clinics and consumer markets, the syndicate’s early bets on foundational technologies like BIOS’ neural interface could yield outsized impact—and returns.

The next phase will likely see the syndicate expanding its portfolio into adjacent areas: cognitive augmentation, sensory enhancement, and AI-powered personalized medicine platforms. It may also evolve into a more structured fund or SPV vehicle as the space matures and institutional capital begins to flow more heavily into human augmentation.

Ultimately, the syndicate’s influence will grow not just through financial returns, but by shaping the norms, standards, and expectations for what human augmentation can—and should—become. In a world where the line between human and machine is blurring, the Human Augmentation Syndicate is helping to write the first chapters of that future.

Sources

Frequently Asked Questions

Who founded Human Augmentation Syndicate?

Human Augmentation Syndicate was founded by Ariel Poler (Founder).