Eyebiotech is a technology company.
Eyebiotech has raised $65.0M across 1 funding round.
Eyebiotech has raised $65.0M in total across 1 funding round.
Eyebiotech has raised $65.0M in total across 1 funding round.
Eyebiotech's investors include Abingworth, Bain Capital Life Sciences, MRL Ventures Fund, RiverVest, SV Health Investors, Mott Family Capital, Omega Funds.
Eyebiotech Limited (EyeBio) is a clinical-stage, privately held ophthalmology biotechnology company dedicated to developing therapies that protect, restore, and improve vision in patients with sight-threatening eye diseases, particularly retinal conditions like diabetic macular edema (DME) and age-related macular degeneration (AMD).[1][2][3] Its lead product, Restoret™ (EYE103), is an investigational tetravalent, tri-specific antibody agonist targeting the Wnt signaling pathway via frizzled receptor 4 and LRP5 to reduce retinal vascular leakage, currently advancing into Phase 3 trials for DME with promising data showing 80% reduction in retinal thickness and 11.2-letter vision gains.[2][6][7] EyeBio serves patients underserved by existing therapies, solving unmet needs in retinal diseases through a pipeline of clinical and preclinical candidates, bolstered by $130 million in funding and now operating as a subsidiary of Merck (MSD outside the US) following a $3 billion acquisition.[2][4][7]
EyeBio was founded in August 2021 by David R. Guyer, M.D. (CEO and President) and Anthony P. (Tony) Adamis, M.D. (co-founder and Advisory Board chair), in collaboration with SV Health Investors, who provided seed funding and aided leadership recruitment and pipeline initiation.[2][5][7] The duo previously co-founded Eyetech Pharmaceuticals, successfully developing and commercializing the first anti-VEGF drug (Macugen) for wet AMD in 2005, establishing their track record in ophthalmology innovation.[5] Early traction included a $65 million Series A round to build a diversified pipeline, leveraging operations in the US and UK for clinical development in an innovation-friendly environment.[2][5] Merck's acquisition in 2024 (up to $3 billion) marked a pivotal moment, integrating EyeBio's assets like Restoret into Merck's resources for accelerated global advancement.[2][4][7]
EyeBio rides the wave of Wnt pathway modulation in ophthalmology, targeting vascular leakage as a foundational driver of retinal diseases amid rising diabetes prevalence and aging populations, where current anti-VEGF therapies fall short for many patients.[2][5][6] Timing aligns with post-2021 biotech funding recovery and AI-driven drug discovery acceleration, but EyeBio's edge lies in its founders' validated translational approach from prior AMD success.[5][7] Market forces favor it: high unmet need in DME/AMD (global Phase 3 success rates ~62%), plus Merck's infrastructure amplifying influence in a $20B+ ophthalmology market.[4][6] As a Merck subsidiary, EyeBio shapes the ecosystem by validating novel biologics, potentially expanding Wnt agonists beyond eyes and partnering with innovators for in-licensing.[2][4]
EyeBio's Merck integration positions it for blockbuster potential with Restoret's Phase 3 readouts expected post-2025, alongside pipeline expansion into wet AMD and beyond, targeting 2027+ approvals amid Wnt's rising prominence.[6][7][8] Trends like precision biologics and combo therapies with anti-VEGFs will propel growth, evolving EyeBio from nimble startup to pharma powerhouse influencing retinal standards worldwide—echoing its founders' Eyetech legacy in redefining eye disease treatment.[2][5]
Eyebiotech has raised $65.0M across 1 funding round. Most recently, it raised $65.0M Series A in February 2022.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Feb 1, 2022 | $65.0M Series A | Abingworth, Bain Capital Life Sciences, MRL Ventures Fund, RiverVest, SV Health Investors, Mott Family Capital, Omega Funds |