Editas Medicine is a technology company.
Editas Medicine has raised $163.0M across 2 funding rounds.
Key people at Editas Medicine.
Editas Medicine has raised $163.0M in total across 2 funding rounds.
Key people at Editas Medicine.
Editas Medicine is a pioneering gene editing company developing transformative, durable, precision in vivo genomic medicines using CRISPR/Cas9 and CRISPR/Cas12a technologies for serious diseases.[1][2][3] It focuses on discovering, developing, manufacturing, and commercializing one-time therapies targeting conditions like high LDL cholesterol, sickle cell disease, beta thalassemia, and oncology indications through partnerships.[1][2][3] The company serves patients with serious genetic diseases worldwide, solving the problem of faulty genes by enabling precise in-body edits; its lead program, EDIT-401, demonstrated over 90% LDL-C reduction in non-human primates from a single dose, with an IND filing planned by mid-2026 and human proof-of-concept by year-end.[2] Growth momentum includes nominating EDIT-401 in September 2025, strong preclinical data presentations at AHA and ESGCT, and a cash runway into Q2 2027.[1][2]
Editas Medicine emerged from foundational CRISPR innovations, exclusively licensing Broad Institute’s Cas12a patent estate and Broad Institute/Harvard University’s Cas9 estates for human medicines.[1][2][3] Founded to translate these genome editing systems into therapies, the company is headquartered in Cambridge, MA, with a site in Boulder, CO, and has evolved from early research into a pipeline-focused clinical-stage firm.[3] Key leadership includes President and CEO Gilmore O’Neill, driving progress toward in vivo candidates, and experts like Linda A. Clayton with 35+ years in biotech, contributing to approved drugs like Tysabri® and late-stage candidates.[3] Pivotal moments include Q2 2025 data validating its gene upregulation and LNP delivery platforms, and Q3 nomination of EDIT-401 as its first in vivo lead.[1][2]
Editas rides the CRISPR gene editing wave, capitalizing on maturing in vivo delivery tech amid surging demand for one-time cures over chronic treatments for genetic diseases.[1][2][3] Timing aligns with regulatory progress (e.g., FDA approvals for prior CRISPR therapies) and market forces like aging populations driving cardiovascular needs—LDL-C programs like EDIT-401 address massive unmet needs in hypercholesterolemia.[2] It influences the ecosystem by advancing accessible genomic medicines, partnering with pharma giants, and pioneering upregulation/LNP combos that could expand CRISPR beyond rare diseases to common ones, accelerating industry-wide adoption.[1][3]
Editas is poised to IND-file EDIT-401 by mid-2026, targeting human data by year-end and potential best-in-class LDL-C therapy amid booming cardiometabolic gene editing demand.[2] Trends like refined LNPs, multi-disease CRISPR expansion, and partnerships will shape its path, potentially evolving it into a commercial leader if proof-of-concept holds. This positions Editas to repair broken genes at scale, fulfilling its mission to transform lives for millions with serious diseases.[1][3]
Editas Medicine has raised $163.0M in total across 2 funding rounds.
Editas Medicine's investors include 5AM Ventures, Dave Maki, ARCH Venture Partners, Atlas Venture, Biomatics Capital Partners, Flagship Ventures, Polaris Partners, Samsara BioCapital.
Editas Medicine has raised $163.0M across 2 funding rounds. Most recently, it raised $120.0M Series B in August 2015.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Aug 1, 2015 | $120.0M Series B | 5AM Ventures, Dave Maki, ARCH Venture Partners, Atlas Venture, Biomatics Capital Partners, Flagship Ventures, Polaris Partners, Samsara BioCapital | |
| Nov 1, 2013 | $43.0M Series A | 5AM Ventures, Dave Maki, ARCH Venture Partners, Atlas Venture, Flagship Ventures, Polaris Partners, Samsara BioCapital |
