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§ Private Profile · Tokyo, Tokyo, Japan
Cancer diagnostics company developing urine-based microRNA biomarker tests with AI for early detection, detecting over 10 cancer types simultaneously.
Based in Tokyo, Japan, Craif develops urine-based cancer screening tests that utilize microRNA biomarkers and artificial intelligence to detect early-stage malignancies. The company's proprietary nanomaterial platform analyzes biological signals to identify more than ten different cancer types simultaneously, supported by an accumulated database of more than 42,000 biospecimens. Operating with a workforce of 51 to 100 employees, the enterprise distributes its miSignal testing services through a network of over 1,000 medical institutions and 500 pharmacies across Japan, experiencing 500 to 600 percent annual sales growth domestically. Craif has raised approximately $57 million in cumulative funding, including a recent $22 million Series C round, backed by institutional investors such as Daiwa House Industry, Aozora Bank Group, and Tokio Marine Holdings. The biotechnology organization was founded in 2018 by co-founder and chief executive officer Ryuichi Onose.
Craif has raised $42.0M across 2 funding rounds.
Craif has raised $42.0M in total across 2 funding rounds.
Craif has raised $42.0M across 2 funding rounds. Most recently, it raised $22.0M Series C in April 2025.
| Date | Round | Lead Investors | Other Investors | Status |
|---|---|---|---|---|
| Apr 28, 2025 | $22M Series C | — | — | Announced |
| Dec 1, 2024 | $20M Series C | — | Dreamers VC, Pioneer Fund, Polychain Capital, Polygon Labs, Visionaire Ventures, Kevin LIN | Announced |
Craif has raised $42.0M in total across 2 funding rounds.
Craif's investors include Dreamers VC, Pioneer Fund, Polychain Capital, Polygon, Visionaire Ventures, Kevin Lin.
Craig Technologies is a U.S.-based aerospace and defense engineering firm founded in 1999, specializing in multidisciplinary engineering services, software design and development, systems engineering and integration, IT support, cybersecurity, training and courseware development, and space and test range operations.[1][2][4][5] Headquartered in Cape Canaveral, Florida (with operations in Merritt Island), it serves government clients like NASA and commercial customers nationwide, employing 210-270 people with annual revenues estimated at $65.6-117.4 million as of 2024, reflecting stable growth from a single-person startup.[1][2][6] As a certified minority-owned, woman-owned, service-disabled veteran-owned small business (ISO 9001/AS9100 and ITAR compliant), it solves mission-critical challenges in spaceflight, defense, and prototyping by delivering end-to-end solutions from concept to real-world application.[2][3][5]
The company maintains strong growth momentum through long-term NASA contracts, diversification into commercial aerospace, and expansion to over 20 states, with revenue per employee around $385,000 indicating operational efficiency.[1][2]
Craig Technologies was founded in 1999 by Carol Craig, who serves as CEO and CFO, starting as a one-person operation in Florida driven by her determination—"I don’t like being told I can’t do something."[2] A service-disabled veteran, Craig grew the firm over a decade to over 450 associates at its peak, diversifying from initial engineering services into aerospace and defense with a focus on commercial opportunities, while maintaining certifications as a U.S.-owned, minority-owned, woman-owned, and economically disadvantaged small business.[1][2][3]
Early traction came from government contracts, including longstanding NASA support for human spaceflight, evolving into a nationwide presence with Top Secret facility clearance and contributions to projects like the International Space Station and Orion CDH.[2][5][6] Pivotal moments include achieving ISO/AS9100 certification and ITAR compliance, enabling mission-critical work in space and defense.[3]
Craig Technologies rides the resurgence in U.S. space exploration and defense modernization, fueled by NASA's Artemis program, commercial space ventures, and rising geopolitical demands for secure aerospace tech.[1][2][5] Its timing aligns with a booming market for small, agile contractors amid supply chain shifts post-COVID and increased DoD/ITAR-compliant needs, where it fills gaps in systems integration and cybersecurity for missile defense, unmanned systems, and test ranges.[3][4][5]
Market forces like federal budget growth for space (e.g., NASA contracts) and defense spending favor its niche, enabling influence through prototyping and training that accelerate programs like human spaceflight.[2][5] By supporting nationwide initiatives, it bolsters the ecosystem for primes like those in avionics and simulation, competing effectively with firms like QinetiQ or MTSI via specialized, cost-effective services.[4]
Craig Technologies is poised for sustained expansion amid escalating space commercialization and defense tech demands, potentially growing revenues through deeper NASA/DoD integrations and new commercial satellite/test range contracts.[1][2][5] Trends like autonomous systems, advanced cyber defenses, and Artemis lunar missions will shape its trajectory, leveraging its veteran/woman-owned status for set-aside opportunities.[3][4]
Its influence may evolve by spinning off innovations (e.g., via founder Carol Craig's Sidus Space ties) or acquiring capabilities in AI-driven simulation, solidifying its role from startup underdog to key ecosystem enabler—proving that mission-focused engineering thrives in high-stakes aerospace.[2][6]