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Founded in 2012, Cintrifuse is a Cincinnati, Ohio-based nonprofit public-private partnership that supports the regional entrepreneurship ecosystem by connecting high-growth startups with corporate businesses, research institutions, mentors, and institutional investors. The organization coordinates regional resources to build a sustainable innovation economy, offering specialized initiatives like venture velocity programs for early-stage founders and thematic labs for corporate development. Operating with a staff of 33 employees and generating approximately $5.4 million in annual revenue, the entity has raised a total of $55.68 million to fund its ongoing operations and grant programs. Through its dedicated investment arm, Cintrifuse Capital, the organization provides direct financial backing to promising regional technology startups operating across the cybersecurity, data pipeline, insurtech, and human resources sectors. Its network of supported portfolio companies features recognizable regional startups such as Level 6, Pantomath, Obai, and Cloverleaf.
Key people at Cintrifuse.
Key people at Cintrifuse.
Cintrifuse Capital is a venture capital firm based in Cincinnati, Ohio, dedicated to supporting early-stage technology companies in the region through direct investments and a fund-of-funds strategy.[1][2][4] Its mission centers on driving local impact and returns by backing high-growth Cincinnati startups, providing access to capital, talent, and networks, while investing in national venture funds to attract broader innovation to the Midwest.[1][3][4] The investment philosophy combines direct funding for Pre-Seed, Seed, and Series A stages—typically $250,000 to $500,000—with support services like talent networks, corporate partners, and an angel network for education and deal flow.[1][2] Key sectors include technology, software (enterprise and consumer), and consumer brands, fostering the Cincinnati startup ecosystem's growth.[1]
Cintrifuse was founded in 2012 as an Ohio-based fund manager to bolster entrepreneurship and innovation in Cincinnati.[5] It evolved from a regional support organization into Cintrifuse Capital, emphasizing venture capital with a dual approach: direct investments in local startups and fund-of-funds targeting top-tier VCs interested in the Midwest.[1][4] Key figures include Joseph Delworth (Venture Capital Analyst), Max Dworin (Vice President), and Santiago García (Principal), who drive operations from the Cincinnati headquarters at 1311 Vine Street.[2][5] Pivotal moments include launching initiatives like the Cintrifuse Capital Angel Network and public investment updates during record-breaking StartupCincy Week in October 2024, alongside recent activity such as the January 2025 Seed VC investment in Nichefire.[2]
Cintrifuse Capital rides the trend of regional venture ecosystems gaining traction amid Midwest tech resurgence, where cities like Cincinnati leverage lower costs and talent pools to compete with coastal hubs.[1][4] Timing aligns with rising interest in diversified U.S. innovation outside Silicon Valley, amplified by events like StartupCincy Week drawing record crowds.[2] Market forces favoring it include corporate interest in Midwest startups and the need for early-stage capital in underserved areas, helping startups overcome funding gaps.[1] It influences the ecosystem by channeling national venture dollars locally, nurturing high-potential companies, and promoting economic prosperity through innovation.[3][4]
Cintrifuse Capital is poised to expand its portfolio with ongoing direct investments and fund commitments, building on 2025 momentum like the Nichefire deal amid a robust pipeline.[2] Trends such as AI-driven software and consumer tech will shape its focus, alongside deeper Midwest VC co-investments to scale regional exits.[1][2] Its influence may evolve by strengthening Cincinnati as a venture hub, potentially managing larger funds and attracting more national players, ultimately amplifying local startup successes on a broader stage—reinforcing its role as the catalyst for Cincinnati's tech ascent.[4][5]
Cintrifuse has 4 tracked investments across 2 companies. The latest tracked deal is $215.0M Series C in Enable Injections in January 2022.
| Date | Company | Round | Lead Investor(s) | Co-Investor(s) |
|---|---|---|---|---|
| Jan 29, 2022 | Enable Injections | $215.0M Series C | Magnetar Capital | Cincinnati Children, CincyTech USA, GCM Grosvenor, Ohio Innovation Fund, Squarepoint Capital, Woody Creek Capital Partners |
| Dec 1, 2019 | VNDLY | $35.0M Series B | Insight Partners | 01 Advisors, ACT ONE Ventures, Album VC, Battery Ventures, Bowery Capital, BoxGroup, Greylock, Hannah Grey, Hyde Park Venture Partners, Indicator Ventures, Scott Sandell, OAK HC/FT, Pelion Venture Partners, Poplar Ventures, Smash Capital, Y Combinator, Aaron Skonnard, Gokul Rajaram, Greg Brockman, Henry Kravis, Epic Ventures, ServiceNow Ventures |
| Feb 1, 2019 | VNDLY | $11.0M Series A | Battery Ventures, Hyde Park Venture Partners | 01 Advisors, ACT ONE Ventures, Bowery Capital, BoxGroup, Greylock, Hannah Grey, Indicator Ventures, Poplar Ventures, Y Combinator, Gokul Rajaram, Greg Brockman, Henry Kravis, Chris Calder |
| Oct 5, 2016 | Enable Injections | $30.0M Series A | Simone Song | BOB COY, Cincinnati Children, Ohio Innovation Fund |