Cellvie is a technology company.
Cellvie is pioneering Therapeutic Mitochondria Transplantation, a novel treatment approach aimed at cellular energy metabolism, deriving medicines from cells and leveraging mitochondria.
Cellvie has raised $11.0M across 2 funding rounds.
Cellvie has raised $11.0M in total across 2 funding rounds.
Cellvie has raised $11.0M in total across 2 funding rounds.
Cellvie's investors include Avoro Ventures, Canaan Partners, Polaris Partners, Taiho Ventures.
Cellvie is a biotechnology company pioneering Therapeutic Mitochondria Transplantation (TMT), a platform technology that augments and replaces dysfunctional mitochondria to restore cellular energy metabolism.[1][2][5][7] It primarily targets ischemia-reperfusion injury—a leading cause of death in conditions like heart attacks, strokes, organ transplantation, and long surgeries—with its lead application in kidney transplants to reduce delayed graft function affecting up to 50% of recipients.[1][2][5][7] The company serves patients in critical care and transplant settings, addressing root causes of cellular failure where current treatments fall short, while exploring broader uses in aging-related degeneration.[1][2][7] Founded in 2018 in Zurich, Switzerland, Cellvie has raised over $10.5 million from investors like Taiho Ventures and Kizoo Technology Capital, employing about 9 people with growing momentum toward clinical development.[2][6]
Cellvie emerged as a spin-out from Harvard Medical School, leveraging breakthroughs in mitochondrial biology to translate research into therapeutics.[4] Founded in 2018 and headquartered in Zurich, Switzerland, the company was established to commercialize TMT, initially focusing on ischemia-reperfusion injury after recognizing mitochondria's role as the "powerhouses of the cell" in energy failure during events like heart attacks and transplants.[1][2][4][5][7] Key leadership includes Alexander Schueller as CEO, supported by a team of experts in science, regulatory affairs, manufacturing, and business.[4][6] Early traction came from partnerships with investors like Taiho Ventures and Kizoo Technology Capital, securing over $10.5 million in funding to advance its platform from preclinical stages toward clinical applications, including kidney transplantation where demand is acute with 12 patients dying daily on waitlists.[2][6][7]
Cellvie rides the mitochondrial medicine and longevity biotech wave, targeting mitochondrial dysfunction as a core driver of acute injuries and age-related diseases amid rising organ shortages and aging populations.[1][7] Timing aligns with advances in cell therapies and gene editing, where ischemia-reperfusion remains a top global killer without root-cause solutions, amplified by post-pandemic focus on transplant success (e.g., 50% delayed graft function in kidneys).[2][5][7] Market forces like Switzerland's biotech hub status, Harvard lineage, and investor interest in "hacking aging" (e.g., via European longevity startups) favor it.[1][2][4] Cellvie influences the ecosystem by pioneering TMT as a platform, potentially enabling collaborations in co-development and licensing to tackle intractable conditions.[5][6]
Cellvie's path forward centers on clinical trials for kidney transplant TMT to prove efficacy in reducing delayed graft function, followed by expansion to heart attacks, strokes, and aging applications like sarcopenia.[1][2][7] Trends in personalized cell therapies, AI-driven longevity, and organ tech will shape its growth, with mitochondrial platforms gaining traction as "new modalities" for degenerative diseases.[1][6][7] Its influence could evolve from niche spin-out to ecosystem leader via partnerships, potentially scaling impact as transplant demands surge globally—reinforcing its mission to save and restore lives through cellular energy revival.[5][6][7]
Cellvie has raised $11.0M across 2 funding rounds. Most recently, it raised $5.0M Seed in September 2025.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Sep 1, 2025 | $5.0M Seed | Avoro Ventures, Canaan Partners, Polaris Partners, Taiho Ventures | |
| Feb 1, 2023 | $6.0M Seed | Avoro Ventures, Canaan Partners, Polaris Partners, Taiho Ventures |