CardioKinetix is a technology company.
CardioKinetix has raised $109.0M across 4 funding rounds.
CardioKinetix has raised $109.0M in total across 4 funding rounds.
CardioKinetix has raised $109.0M in total across 4 funding rounds.
CardioKinetix's investors include Johnson & Johnson Innovation, New Leaf Venture Partners, Saints Capital, SV Health Investors, Third Rock Ventures, VantagePoint Capital Partners, U.S. Venture Partners.
CardioKinetix is a medical device company developing the Parachute Ventricular Partitioning Device, a catheter-based implant for treating heart failure patients with left ventricular dilation following an anterior myocardial infarction.[1][2][3][4] The device isolates the damaged heart region to reduce chamber volume, improve cardiac output, and restore ventricular function, serving cardiologists and patients with ischemic heart failure where treatment options are limited.[1][4][5] Founded in 2002 and based in Menlo Park, California, the company raised $118.8M across stages up to Series F, with the last round in 2015, and reached milestones like 500 implants by 2016 while enrolling in a U.S. pivotal trial.[1][5]
CardioKinetix was founded in 2002 in Menlo Park, California, focusing on innovative percutaneous treatments for heart failure caused by post-myocardial infarction left ventricular dilation.[1][2] The core idea emerged from addressing the unmet need for minimally invasive options: after a heart attack, ventricular enlargement reduces cardiac output, leading to symptoms like shortness of breath and fatigue, with few effective therapies available.[4][5] Early development centered on the Parachute device, pioneering catheter-based partitioning of damaged myocardium, which gained traction through clinical studies showing high procedural success (96%) and sustained ventricular improvements at 12 months.[4] Pivotal moments included selection as a "Fierce 15" company, reaching 500 implants across 15+ countries by 2016, and initiating the landmark U.S. PARACHUTE IV randomized trial under FDA investigational device exemption.[2][5][6]
CardioKinetix rides the trend of percutaneous cardiac interventions amid rising heart failure prevalence—driven by aging populations and post-MI complications—where minimally invasive devices reduce surgical risks and costs.[4][5] Timing aligns with advances in catheter delivery and imaging, enabling precise partitioning amid a market favoring outpatient-compatible therapies over invasive LVADs.[1][4] Favorable forces include growing demand for heart failure solutions (a "fast-growing unmet need" per experts) and regulatory progress via IDE trials, influencing the ecosystem by expanding options for tens of thousands of patients and potentially lowering healthcare burdens through improved outcomes.[4][5] It contributes to medtech innovation in structural heart disease, bridging gaps left by pharmaceuticals and surgery.[1][2]
With its last funding a decade ago and trial data from 2016, CardioKinetix's path likely hinges on PARACHUTE IV completion, potential FDA approval, and commercialization expansion—though current status appears dormant based on available records.[1][5] Rising AI-enhanced imaging and personalized cardiology trends could revive or evolve the Parachute platform for broader adoption. Its influence may grow if acquired or partnered, pioneering ventricular restoration in a heart failure market projected to expand, ultimately delivering the minimally invasive breakthrough promised since 2002.[4][5]
CardioKinetix has raised $109.0M across 4 funding rounds. Most recently, it raised $50.0M Series F in December 2014.