Basking Biosciences is a technology company.
Basking Biosciences has raised $55.0M across 1 funding round.
Basking Biosciences has raised $55.0M in total across 1 funding round.
Basking Biosciences is a clinical-stage biopharmaceutical company developing the first reversible thrombolytic therapy for acute ischemic stroke (AIS), addressing a critical gap where most patients remain ineligible for current treatments.[1][2][4][5] Its lead candidate, BB-031 (also referred to as DTRI-031), is an RNA aptamer that targets von Willebrand Factor (vWF) to dissolve clots and restore blood flow, paired with a rapid reversal agent, BB-025 (or DTRI-025), enabling safer, on-demand control to extend the treatment window.[1][2][4][5] The company serves stroke patients and healthcare providers, solving the problem of limited thrombolytic options by offering rapid-onset, short-acting therapy with reduced bleeding risks.[1][2][4] Growth momentum includes $60.4M total funding, with a $55M recent round, and progression to Part B of the Phase 2 RAISE trial, where first patients were dosed as of October 2025.[2][5]
Founded in 2019 and based in Ohio, US, Basking Biosciences emerged to tackle the unmet need in ischemic stroke therapy for a fast-acting, reversible thrombolytic that reopens arteries in an extended window beyond approved drugs like tPA.[2][3] Co-founder and Chief Medical Officer Shahid M. Nimjee, M.D., Ph.D., a Professor of Neurosurgery and Surgical Director of the Comprehensive Stroke Center at The Ohio State University Wexner Medical Center, drives the scientific vision, rooted in targeting vWF for precise clot disruption.[5] Richard Shea served as CEO from inception until October 2025, when Julia C. Owens, Ph.D.—with prior CEO roles at Ananke Therapeutics and Millendo Therapeutics—took over, transitioning Shea to President and COO for continuity.[5] Early traction built through preclinical development and funding, leading to the ongoing Phase 2 RAISE trial initiation.[2][4][5]
Basking rides the wave of precision medicine in cardiovascular disease, where RNA-based therapies like aptamers enable targeted thrombosis treatment amid rising stroke incidence from aging populations and post-COVID clotting risks.[1][4][5] Timing is ideal: advances in reversal agents address safety barriers in thrombolytics, coinciding with demands for extended treatment windows as stroke care evolves toward comprehensive centers.[5] Market forces favor it, including a massive unmet need (most AIS patients untreated) and biopharma interest in short-acting biologics.[2][5] Basking influences the ecosystem by pioneering reversible antithrombotics, potentially reshaping stroke guidelines and inspiring similar paired therapies in thrombosis.[1][4]
Basking is poised for Phase 2b advancement of BB-031, leveraging new CEO Julia Owens' experience to unlock the remaining $27.5M from recent funding and pursue partnerships for late-stage trials or commercialization.[5] Trends like AI-driven stroke detection and expanded endovascular access will amplify its impact, while regulatory emphasis on safety could fast-track approval if reversal data shines. Its influence may grow by setting a new standard for controllable thrombolytics, transforming AIS from a time-bound crisis to a more accessible intervention—echoing its mission to redefine thrombosis care from the outset.[4][5]
Basking Biosciences has raised $55.0M in total across 1 funding round.
Basking Biosciences's investors include ARCH Venture Partners, Domain Associates, Lu Wang, Illumina Ventures, Johnson & Johnson Innovation, Vertex Ventures.
Basking Biosciences has raised $55.0M across 1 funding round. Most recently, it raised $55.0M Series A in January 2024.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Jan 1, 2024 | $55.0M Series A | ARCH Venture Partners, Domain Associates, Lu Wang, Illumina Ventures, Johnson & Johnson Innovation, Vertex Ventures |