Adicet Bio, Inc is a company.
Adicet Bio, Inc is a company.
Adicet Bio, Inc has raised $25.0M across 1 funding round.
Key people at Adicet Bio, Inc.
Adicet Bio, Inc has raised $25.0M in total across 1 funding round.
Adicet Bio, Inc has raised $25.0M in total across 1 funding round.
Adicet Bio, Inc's investors include Endeavor Venture Funds.
Key people at Adicet Bio, Inc.
Adicet Bio, Inc. is a clinical-stage biotechnology company developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer.[1][2] Its lead product candidate, ADI-001, is a first-in-class investigational gamma delta CAR T cell therapy targeting autoimmune indications like lupus nephritis (LN), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), idiopathic inflammatory myopathy (IIM), stiff person syndrome (SPS), and anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV).[1] ADI-001 serves patients with severe autoimmune diseases by enabling robust B-cell depletion, tissue homing, and durable activity through an off-the-shelf approach, addressing limitations of autologous therapies like manufacturing delays and patient variability.[1][2] The company demonstrates growth momentum via FDA Fast Track Designation for ADI-001 in relapsed/refractory class III/IV LN in June 2024 and an ongoing Phase 1 study, alongside a pipeline of engineered gamma delta T cells for broader applications.[1]
Adicet Bio emerged from advancements in gamma delta T cell research, positioning itself as a leader in allogeneic cell therapies since its early work highlighted in 2019 posters on T-cell receptor-like antibodies for solid tumors.[1] The company's evolution reflects a shift from oncology-focused efforts—evidenced by initial Phase 1 oncology safety data—to prioritizing autoimmune diseases, leveraging gamma delta T cells' innate properties for "off-the-shelf" accessibility.[1][2] Key milestones include developing its novel platform for CAR-engineered gamma delta T cells, with pivotal oncology data supporting expansion into autoimmune trials, and recent operational moves like inducement grants under Nasdaq rules as of November 2025.[2]
Adicet Bio stands out in the cell therapy space through these key advantages:
Adicet Bio rides the explosive growth in cell therapies for autoimmune diseases, a trend accelerated by autologous CAR-T successes in lupus and beyond, but hindered by scalability issues.[1] Timing is ideal amid surging demand for allogeneic options, as market forces like rising autoimmune prevalence (e.g., SLE affecting millions) and regulatory nods like Fast Track favor rapid entrants.[1] The company influences the ecosystem by pioneering gamma delta T cells—positioned as a "new generation" of immune therapies—potentially lowering costs, improving access, and expanding beyond oncology to chronic conditions, challenging incumbents reliant on personalized manufacturing.[1][2]
Adicet Bio is poised for Phase 1 readouts on ADI-001 across its autoimmune basket, with potential expansions into additional indications or oncology pivots based on data.[1] Trends like refined CAR engineering and combo regimens will shape its path, amplifying gamma delta T cells' role in making cell therapy mainstream and off-the-shelf standard.[2] Its influence could evolve from pipeline pioneer to market leader if durability and safety hold, ultimately delivering accessible therapies that transform autoimmune care—echoing its mission to fight cancer and autoimmunity with best-in-class innovation.[1][2]
Adicet Bio, Inc has raised $25.0M across 1 funding round. Most recently, it raised $25.0M Series B in August 2019.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Aug 1, 2019 | $25.0M Series B | Endeavor Venture Funds |
