Abalos Therapeutics is a technology company.
Abalos Therapeutics is a technology company.
Abalos Therapeutics has raised $36.0M across 1 funding round.
Abalos Therapeutics has raised $36.0M in total across 1 funding round.
Abalos Therapeutics has raised $36.0M in total across 1 funding round.
Abalos Therapeutics's investors include Coparion, High-Tech Gründerfonds, Seventure Partners.
Abalos Therapeutics is a German biotechnology company developing novel anti-cancer therapies using a proprietary Adapt Innate platform based on arenaviruses to trigger comprehensive immune responses against solid tumors and metastases.[1][2] Their lead candidate, ABX-001, is a systemically administered, non-oncolytic immunotherapy that persists in cancer and antigen-presenting cells, engaging both innate and adaptive immunity to uncloak tumors without destroying healthy cells; it dosed its first patient in a Phase 1 trial for solid tumors in October 2025.[1][3] The company serves oncology patients by addressing immunotherapy resistance, with strong preclinical data published in Cell Reports Medicine and plans for a pipeline of naturally optimized and payload-carrying therapeutics.[1][3]
Founded in 2019, Abalos has raised €43 million in Series A funding and achieved key milestones like appointing experienced executives and securing German government funding, positioning it for clinical advancement amid rising demand for innovative cancer immunotherapies.[2][3]
Abalos Therapeutics launched in October 2019 with a €12 million Series A round to pioneer immuno-virotherapies against cancer, leveraging arenaviruses' immunostimulatory properties.[1][3] The founding team comprises experienced entrepreneurs and scientists focused on reactivating the full immune system against solid tumors, building on proprietary technology to create a new class of product candidates.[1] Early traction included expanding the leadership team with drug development and viral therapy experts in February 2020, followed by a Series A extension in 2021 totaling €43 million.[3] Pivotal moments encompass appointing Thomas Bogenrieder as Chief Medical Officer in 2022, securing KMU-innovativ funding from Germany's Federal Ministry of Education and Research in 2024, and naming Gerben Moolhuizen as CEO in October 2024.[3]
Abalos rides the cancer immunotherapy wave, particularly the shift toward viral-based platforms that address limitations of checkpoint inhibitors and CAR-T therapies by inducing broad, durable responses in "cold" solid tumors.[1][3] Timing aligns with surging investment in immuno-oncology—post-2020 funding booms and regulatory nods for viral therapies—bolstered by market forces like aging populations and unmet needs in metastatic cancers.[1][2] By validating arenavirus approaches in peer-reviewed studies and combinations, Abalos influences the ecosystem, potentially expanding virotherapy adoption and fostering synergies with T-cell engagers or payloads.[1][3]
Abalos is poised for Phase 1 readouts in 2026, with events like CICON 2025 showcasing data to partners and investors; pipeline expansion into payload-carrying candidates could accelerate toward later-stage trials.[1][3] Trends like AI-optimized viruses and combo immunotherapies will shape its path, amplifying impact as resistance mechanisms are cracked. Its evolution from startup to clinical player underscores biotech's high-stakes innovation, delivering on the promise of systemic tumor uncloaking for broader patient access.[1][3]
Abalos Therapeutics has raised $36.0M across 1 funding round. Most recently, it raised $36.0M Series A in October 2021.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Oct 1, 2021 | $36.0M Series A | Coparion, High-Tech Gründerfonds, Seventure Partners |