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§ Private Profile · Durham, NC, USA
Medical device company developing LifeFlow systems for rapid fluid and blood infusion in emergency and critical care settings.
Based in Durham, North Carolina, 410 Medical is a medical device company that develops rapid fluid and blood infusion systems for emergency and critical care. The company's flagship product, the LifeFlow Rapid Infusion System, is a handheld device designed to help healthcare providers quickly administer intravenous fluids to patients experiencing shock, sepsis, or trauma. Operating with a team of 21 employees, the organization has seen its devices utilized in the treatment of over 20,000 patients across various healthcare settings. 410 Medical has raised more than $14 million in total venture funding, which includes a $7.5 million Series B round closed in late 2022. The enterprise is backed by a syndicate of institutional investors and strategic partners, including Hatteras Venture Partners, Orlando Health Ventures, OSF Healthcare, and WakeMed. 410 Medical was founded in 2013 by Mark Piehl and Luke Roush.
410 Medical has raised $38.5M across 6 funding rounds.
410 Medical has raised $38.5M in total across 6 funding rounds.
410 Medical has raised $38.5M in total across 6 funding rounds.
410 Medical's investors include Hatteras Venture Partners, Toba Capital, Stan Lynall, Sovereign's Capital, AIM Group, Kleinheinz Capital, North Carolina Venture Capital Multiplier Fund, WakeMed Hospitals, Triangle Venture Alliance, Bios Partners, Luke Roush.
410 Medical is a medical device company specializing in critical care resuscitation tools, primarily the LifeFlow PLUS, a hand-operated rapid infuser that delivers blood or fluids quickly to patients in shock, sepsis, trauma, or hypotension[1][2]. It serves emergency medical services, hospitals, military operations, and pediatric care providers, solving the problem of slow, complex existing infusers that hinder efficient volume resuscitation for critically ill patients[1][2]. Founded in 2013 and based in Research Triangle Park, North Carolina, the company has raised $39.82M, holds 13 patents in areas like fluid dynamics and intensive care, and reports saving nearly 35,000 patients to date, with products now on the market demonstrating steady growth momentum[1][2].
410 Medical was founded in 2013 by an entrepreneur inspired by real-world gaps in emergency medicine, starting development of the LifeFlow infuser in his garage after observing inadequate tools for rapid fluid delivery during critical resuscitations[1]. Drawing from personal experiences in high-stakes environments, the founder aimed to equip paramedics, nurses, PAs, and doctors with simpler, faster devices to improve patient outcomes in scenarios like trauma or post-surgical hemorrhaging[1]. Early traction came from pivotal moments, such as paramedics using LifeFlow to save a young girl hemorrhaging after a tonsillectomy, validating the device's life-saving potential and driving adoption in hospital, transport, and military settings[1][2].
410 Medical rides the trend of innovative medical devices enhancing emergency and critical care, particularly amid rising demands for rapid intervention in trauma, sepsis, and military field medicine where seconds matter[1][2]. Timing aligns with advances in fluid dynamics and a push for portable, non-electric tools resilient in austere environments like battlefields or ambulances, countering limitations of traditional pumps[1]. Market forces favoring it include growing recognition of resuscitation's role in reducing mortality—e.g., in pediatric and shock cases—and expansion in biotech hubs like North Carolina's Research Triangle Park[1][2]. By influencing protocols in EMS and military healthcare, it shapes ecosystem standards for faster, more reliable infusion tech.
Next for 410 Medical involves scaling LifeFlow adoption globally, leveraging its $39.82M funding and patent portfolio to penetrate more hospital networks and defense contracts while iterating on PLUS enhancements[1]. Trends like AI-assisted diagnostics and portable medtech will amplify its edge, especially as aging populations and conflict zones drive demand for resuscitation innovation. Its influence may evolve from niche lifesaver to standard in critical care protocols, potentially through partnerships or acquisitions—building on a garage-born idea that's already transformed emergency outcomes.
410 Medical has raised $38.5M across 6 funding rounds. Most recently, it raised $14.0M Series B in March 2025.
| Date | Round | Lead Investors | Other Investors | Status |
|---|---|---|---|---|
| Mar 1, 2025 | $14M Series B | — | Hatteras Venture Partners, Toba Capital | Announced |
| May 1, 2023 | $8M Series B | — | Hatteras Venture Partners, Toba Capital | Announced |
| Oct 1, 2019 | $8M Series A | Hatteras Venture Partners | Toba Capital, Stan Lynall, Sovereign's Capital | Announced |
| Aug 22, 2018 | $3.1M Venture Round | AIM Group | Kleinheinz Capital, North Carolina Venture Capital Multiplier Fund, WakeMed Hospitals | Announced |
| Jun 21, 2017 | $2.1M Series A Plus | Triangle Venture Alliance | — | Announced |
| Mar 23, 2017 | $3.3M Series A | Bios Partners | Luke Roush | Announced |