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3Z Pharmaceuticals has raised $400K across 1 funding round.
Key people at 3Z Pharmaceuticals.
3Z Pharmaceuticals has raised $400K in total across 1 funding round.
Based in Reykjavik, Iceland, 3Z Pharmaceuticals is a contract research organization that specializes in high-throughput drug screening for central nervous system disorders using zebrafish models. The biotechnology company provides in vivo efficacy and toxicity assays to pharmaceutical clients developing therapeutics for neurological conditions such as epilepsy, Parkinson's disease, insomnia, and ADHD. Operating with a core team of five key members, the firm utilizes a proprietary software and laboratory platform capable of parallel screening up to 2,500 zebrafish larvae to rapidly identify novel drug candidates. The enterprise has raised a $400,000 seed funding round backed by a syndicate of investors that includes Swiss biotech firms Baliopharm and Probiocon, alongside NSA Ventures and Sigþór Sigmarsson. 3Z Pharmaceuticals was founded in 2008 by Karl Ægir Karlsson and Haraldur Þorsteinsson.
3Z Pharmaceuticals is a biotech company based in Reykjavik, Iceland, specializing in drug discovery and development for central nervous system (CNS) disorders using a proprietary zebrafish screening platform.[1][2][3][4][6] It provides cost-effective, high-throughput services for drug efficacy, toxicity assays, and disease modeling—targeting conditions like ADHD, Parkinson's, epilepsy, sleep disorders, and motor neuron disease—while advancing its own preclinical small molecule candidates, primarily through drug repurposing of existing licensed drugs.[1][2][3][4] The platform enables parallel screening of up to 2,500 zebrafish larvae, offering flexibility, scalability, and custom assays, which accelerates discovery by about three years via existing safety data.[1][4] Originally a contract research organization (CRO), 3Z is shifting toward IP-sharing models and in-house programs, with a lead ADHD asset (non-stimulant) seeking partners and investors.[1][3]
Founded in 2008 by Karl Karlsson and Haraldur Thorsteinsson, 3Z Pharmaceuticals emerged from their 2006 research on zebrafish sleep patterns at Reykjavik University Neurolab.[2] Starting with a focus on sleep research, the company expanded into broader CNS drug discovery, efficacy/toxicity assays, and models for Parkinson's, motor neuron disease, epilepsy, and sleep disorders.[1][2] Early traction came from collaborations with pharma companies, including screening for rare mutations and novel targets, earning recognition as a top European CRO in 2019 for rapid, innovative solutions.[1] This evolution humanizes 3Z as a university spinout leveraging academic breakthroughs into commercial biotech.
3Z rides the wave of advanced disease modeling and behavioral genetics in biotech, where zebrafish enable ethical, scalable alternatives to rodent models for CNS drug screening—a market pressured by high failure rates (90%+ in neurology) and costs exceeding $2B per drug.[1][4][6] Timing aligns with AI-driven drug discovery and repurposing trends, amplified by post-2020 demand for faster CNS therapies amid aging populations and unmet needs in ADHD/epilepsy.[1][2][3] Favorable forces include Iceland's biotech ecosystem, EU grants (e.g., EIT Health), and global push for non-animal testing; 3Z influences by validating repurposed candidates, reducing risks for big pharma, and building AI databases for predictive analytics.[1][5]
3Z's zebrafish edge positions it for partnerships on its ADHD lead and expansion into AI-enhanced screening, potentially unlocking in-house pipelines beyond preclinical stages.[1][2][3] Trends like regulatory nods for zebrafish data, AI in pharma, and CNS repurposing will propel growth, evolving 3Z from service provider to full-fledged therapeutics player—amplifying its role in faster, ethical drug innovation.[1][4]
Key people at 3Z Pharmaceuticals.
3Z Pharmaceuticals has raised $400K in total across 1 funding round.
3Z Pharmaceuticals has raised $400K across 1 funding round. Most recently, it raised $400K Seed in July 2016.
| Date | Round | Lead Investors | Other Investors |
|---|---|---|---|
| Jul 1, 2016 | $400K Seed |